This private blood test measures Beta-CTX (beta-crosslaps, C-terminal telopeptide of type I collagen), the reference biochemical marker of bone resorption. The catalogue test price is £169.38 plus a £50 phlebotomy fee, with results in 5 days.
Because Beta-CTX has a strong circadian rhythm and drops after eating, a morning fasting blood sample (ideally before 10:00 am after an overnight fast) is required for accurate baseline and follow-up comparisons.
Written by Mr Stephen Lingam. Reviewed by Dr Penny Sheehan (GMC 6056535) on 18/10/2026.
Yes. Food significantly lowers Beta-CTX levels, so fast overnight and book a morning appointment (drinking plain water is fine).
Bone turnover markers such as Beta-CTX respond within 3 to 6 months of starting bisphosphonates, denosumab or HRT, long before changes appear on a repeat DEXA scan.
Yes. Avoid high-dose biotin supplements for 48 hours before your blood draw, as biotin can interfere with the immunoassay.
Results are normally returned in 5 working days.